Alentejo, is a region of Southern Portugal that corresponds to one third of the territory of Continental Portugal. It has an area of 31 551.2 km² (33% of the continent) and 760,098 inhabitants (7.4% of Portugal). It is a region with low population density, but with high agricultural potential. The lack of water in this region has been one of the main constraints to its development, limiting the modernization of agriculture and sustainability in the public supply. The Alentejo region is characterized by large precipitation deficit and high intensity of irrigated agriculture. This is an area with high potential for promoting the production and the reuse of reclaimed water in agriculture. The lack of water is thus an opportunity to investigate and support more alternatives that, taking advantage of the available water resources, are sustainable from the economic, social and environmental point of view.